Florida State needs to keep winning big.
Mizzou will get quarterback James Franklin back from an injury this week. Nor can they afford a loss if they want to get to and a possible at-large bid to the BCS, while avoiding a must-win situation when they play the Crimson Tide.
But a win over Penn State is an absolute must. Nebraska kept its Big Ten hopes alive on the miracle desperation pass to beat Northwestern last week, but winning in Ann Arbor with a backup quarterback might taken even more favor from above.
Wisconsin needs to keep winning in their quest to get to and be ranked high enough to get a BCS bowl bid.
The Cougars are not ranked in the current BCS standings, but a win in Madison means we have to give them a serious look in the race for the major bowls.
LSU-Alabama is the first of which. Miami might have taken it on the chin last week in Tallahassee, but if they take care of business against Virginia Tech, the Hurricanes can all but salt away in the ACC Coastal Division and move closer to another crack at Florida State in a neutral-site conference championship game.
Houston-Central Florida will determine the frontrunner for the American Athletic Conference title, a race in which Louisville and Cincinnati are still lurking in. Fresno State is still on pace to qualify for a BCS game, but this trip to Wyoming will not be an easy one.
The Fresno defense, never all that special at its best, is dealing with some injuries in the secondary and the Cowboys can move the ball.